Photodynamic Therapy (PDT) for Actinic Keratosis

An FDA-approved treatment for actinic keratosis. It destroys precancerous lesions across the entire field of sun damage.

Board-certified dermatologist Dr. Craig Singer treats actinic keratosis and other precancerous sun damage at his Bingham Farms practice.

Quick facts

Treats

Actinic keratosis (precancer)
Status
FDA-approved
How it works
Levulan + blue light
Sessions
Usually 2 sessions, 4–6 weeks apart
Healing
Scabs heal by ~day 14
Sun
Avoid sun 48h, stay indoors

What are Actinic Keratosis?

Actinic keratosis are rough scaly patches on the skin caused by chronic sun exposure. They are more common in fair skin/blue-eyed people and are precancerous. If left untreated, actinic keratosis may progress to squamous cell skin cancer. Therefore, early treatment of actinic keratosis will reduce the risk of developing skin cancer. Treatments for Actinic Keratosis include: Fluorouracil, Imiquimod, Picato, Diclofenac, Liquid nitrogen, and PDT.

What is Photodynamic Therapy (PDT)?

PDT is an FDA approved treatment for actinic keratosis. It works through the topical application of a photo sensitizing chemical (Levulan) which is then stimulated by a blue wavelength of light. The chemical reaction subsequently destroys actinic keratosis (i.e. precancerous lesions).

How PDT works

1

Apply Levulan

A photosensitizing chemical (Levulan) is applied to the treatment area.

2

Incubate

It absorbs into the sun-damaged cells over one to two hours.

3

Apply Levulan

A blue wavelength of light activates it, destroying the precancerous lesions.

Craig Singer MD: Skin Care Specialist in Metro Detroit

Recovery snapshot

What the next two weeks usually look like

Patients should plan for visible redness, strict light avoidance, and steady healing. The reaction can look intense, but it is part of the treatment response.

Day 0–2

Bright redness, burning sensation, swelling, and heightened sensitivity to sunlight or bright indoor light.

Day 3

Discomfort usually begins to settle as the acute reaction cools down.

Day 7–14

Crusting, peeling, and scabs typically continue to clear.

Month 1

Skin often feels smoother as actinic keratoses are reduced across the treated field.
Photodynamic Therapy (PDT) FAQs
Clear answers for the procedure day, recovery window, sun precautions, and who should avoid treatment.
  1. PDT is applied to the entire field of sun damage, thereby destroying actinic keratosis that are both visible and microscopic.
  2. The exact areas to be treated are applied by the physician to ensure the accuracy of the treatment.
  3. Scientific studies have shown that people who have undergone PDT have improved skin texture and tone, as well as an improvement in their overall appearance.
  4. In addition, the reaction that develops from PDT often subsides within two weeks whereas the reaction from Fluorouracil or Imiquimod may last longer than four to six weeks.
  5. You will not need to fill a prescription.
  6. No scarring from PDT has been reported to date.
  7. Finally, most Medicare plans cover the cost of PDT through a medical benefit. 
  1. We will lead you to our procedure room and informed consent will be obtained.
  2. We will cleanse your face with alcohol/acetone.
  3. Levulan (a photosensitizing chemical) will be applied to the treatment area.
  4. The Levulan will need to incubate for one to two hours prior to illumination with light. You are permitted to leave the office during the incubation, but you are not permitted to wash your face during this time.

In general, lesions on the face need to incubate for 60 minutes, whereas lesions on the scalp need to incubate for 60 to 120 minutes depending on the thickness of the lesions. In addition, the scalp will be occluded with Saran wrap after application of Levulan to enhance penetration.

On occasion, loose scale or crust will be gently removed from the skin surface.

  1. Once incubation is complete, you will be positioned underneath the U blue light (for 17 minutes) at which time the photodynamic reaction occurs.
  2. It is normal to experience a burning sensation while you are exposed to the light. We will hand you a fan to help cool the area during the treatment. But if the reaction is too intense, we can temporarily pause the treatment. Less than 3% of people discontinue treatment due to severe burning and stinging.
  1. Immediately after the procedure, your skin will look bright red and you may experience a burning sensation.
  2. Over the next 48 hours, it may look like you had a sunburn with swelling.
  3. Areas around the eyes and lips may look more extreme.
  4. Some people experience a more intense reaction with crusting and oozing, followed by skin peeling.
  5. In general, the more intense the reaction, the better the result.
  6. Discomfort usually subsides by day 3.
  7. All scabs will typically heal by day 14.
  8. Over the next couple weeks, you may see some discoloration (lighter or darker areas) which will spontaneously resolve.
  9. Your skin should feel smoother a month after treatment indicating a reduction in actinic keratosis.

Yes. You will be overly sensitive in the sun for 48 hours. It is best to remain indoors. But if you go outside, you must wear a wide brimmed hat and a zinc-based sunscreen (such as Neutrogena Pure and Free baby). Also, try not sit near a window in your home or under a lamp, as this light may produce more burning sensation too. 

  1. Apply ice packs or washcloth with cold water as needed for discomfort.
  2. Use a gentle facial skin cleanser such as Dove sensitive skin soap or Cetaphil.
  3. Use Cerave cream or Cetaphil cream (not lotion) to moisturize OR Vaseline ointment/Aquafor ointment if crusting develops.
  4. Use OTC 1% hydrocortisone ointment twice daily if you are irritated.

Call us at (248) 792-3785 or e-mail at TopDoc@SingerDerm.com if you have questions or concerns.

Most patients will require 2 sessions spaced 4-6 weeks apart.

Those with the following medical conditions should avoid PDT:

  1. History of porphyria
  2. Blood clotting defects
  3. Pregnancy or Nursing
  4. Inability to avoid sun exposure, bright lights for 2 days

Photodynamic therapy across metro Detroit

Dr. Singer performs blue-light photodynamic therapy (PDT) for actinic keratosis and sun-damaged skin at his Bingham Farms office, convenient to patients across Oakland County and metro Detroit. PDT treats the full field of sun damage, including precancers that are not yet visible.

Patient testimonials

4.9

Based on Google reviews

HOUR Detroit Top Doc

Recognized dermatologist

About Dr. Craig Singer MD Dermatology

Located in Bingham Farms, Craig Singer MD Dermatology was founded in 2017 by Dr. Craig Singer, a board-certified dermatologist.

We specialize in medical, surgical and cosmetic dermatology, treating patients of all ages, newborn through elderly. We have expertise in a wide variety of skin conditions including eczema, acne, and warts as well as complicated dermatological issues that include hair loss and autoimmune disease. In addition, we are highly skilled in the evaluation of moles and skin cancer.

For more than 20 years, Dr. Craig Singer has helped thousands of patients look and feel their best.

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20+ Years

Trusted by Thousands

Board-Certified

Dermatologist & Pediatrician

Craig Singer MD: Skin Care Specialist in Metro Detroit
american board of physician specialists
Craig Singer MD: Skin Care Specialist in Metro Detroit
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